Long term ephedrine use reddit. for me, long term stimulant use has been just fine. In my state, its as simple as going to the counter of a Walgreens and asking for Bronchaid (or similar generic with Ephedrine HCL). bbr. 1016/j. Antidepressants gave me permanent sexual and physical damage, so I wont go there. You kids these days, have to be spoon fed Long-term exposure to ephedrine leads to neurotoxicity and neurobehavioral disorders accompanied by up-regulation of CRF in prefrontal cortex and hippocampus in rhesus macaques "Abstract. First off, EC (Ephedrine + Caffeine) is 100% legal OTC and an excellent appetite suppressant. So far I haven't had any issues and I'm pretty sure they are safe to take long term as long as you don't up your dose and don't take them daily. It definitely has a an effect of perking you up. Do not take more of it, do not take it more often, and do not take it for a longer period of time than recommended on the label (usually 7 days), unless otherwise directed by your doctor. I use it to get better effects when I want to get rid of some fat/overall weight, for better focus there are tons of other supplements worth trying. I've taken it for a long time. It shares a lot of its chemical makeup with meth. Jan 4, 2013 · Ephedrine is one of the four active components of the herb Ephedra. L-tryptophan, glycine & GABA always get me to sleep. 2020 Sep 1:393:112796. Take this medicine only as directed. Drugs like Benadryl and other first-generation anti-histamines (when used chronically for long, long periods of time over the lifespan) are actually linked to dementia due to their anti-cholinergic effect. Pregabalin Feel free to skip to the bottom for my questions if you don't want to read my whole backstory :). And 'long term' in this case is like, a year. Like you, I was apprehensive at first about using it due to horror stores (Phen-Phen) and the fact I had to ask the pharmacist for it. Could someone with more chemistry or research background shed light into how bad this is? In a randomized, placebo-controlled, double blind study, 180 obese patients were treated by diet (4. I've always had a RHR of about 100bpm, and it doesn't seem to change when using Bronkaid. You can do it. Ephedrine, ephedrine plus caffeine, and ephedra-containing dietary supplements with or without herbs containing caffeine all promote modest amounts of weight loss Heavier stimulants are really the only direction you can go. I expect blood pressure would be a bit high too. nlm. Long-term use can cause side effects like high blood pressure. I’m very attentive to work-related things, tasks needing done around the home, my surroundings, and conversations, but there is a fine line between positive and This question might be better answered in r/askdrugs or other similiar sub, as ephedrine is not considered a nootropic except by the loosest of definitions. i plan to stay this treatment I only use benzos for anxiety, panic, and sleep now. Do you mean it's something you shouldn't use at all, or do you mean I shouldn't use as much as I do? I never use more than directed on the box. Long-term exposure to ephedrine leads to neurotoxicity and neurobehavioral disorders accompanied by up-regulation of CRF in prefrontal cortex and hippocampus in rhesus macaques "Abstract. This is a dangerous substance - ephedrine causes addiction similar to codeine and amphetamine. People who say they have been using is long term with positive effects are probably also supplementing with healthy diet and other supplements. You are what you eat - so fad diets will not work. Vyvanse helps my short term motivation, but not necessarily my long term motivation (which is required to stick with those creative pursuits and hobbies that require time to perfect). Especially at the doses you're using. The incidence of ephedrine-type kidney stones is small overall (about 0. Curbs appetite and brought up my chronically low body temp to normal. It's never messed with my bp or hr. ephedrine lost the magic, my hunch is that my body needs the full spectrum of alkaloids (even tho ephedrine is the for sure the main one) just like the 90s preworkouts had Thx for the tip! I definately wont use it long term, but there isnt anything else available other than the good old cbt therapy which is highly costly and takes months to produce results. I use it for powerliftingm studying, going out, whenever I want to enter godmode. 141 patients completed this part of the study. The worst, though, is shitting. Amphetamines cause strong appetite suppression even at low doses. Just use ephedirine + caffeine like has been proven to work and proven safe within limits like everything else. That said it will boost blood pressure and is essentially an amphetamine, so it can be addictive and represent a heart risk over the long-term. It has some good effect in the beginning. I tried it for 6 months. Mostly just use it as an appetite suppressant and to wake me up. The two cannot be readily compared due to differences in duration taken, what the side effects are, whether they are overdosed or not, etc. Good luck. Long-term moderate amphetamine usage is mostly harmless. At best studies on coca tea drinkers find minimal to no harm, but they're consuming very low doses of cocaine. The consensus among users appears to be mixed, with some reporting cognitive benefits while others emphasize the risks and side effects associated with its use. Ephedrine, caffeine and aspirin: safety and efficacy for treatment of human obesity https://pubmed. 30, 2001. But all said and done, it’s a gimmick. - in horses found that long-term administration of high doses of clenbuterol increased the expression of genes related to various muscle components and fat metabolism. Two cautions tho. Jan 23, 2020 · I'm curious if anyone has any experience or wisdom about ephedrine & it's use long term? I discovered over a year ago that 25-50mg of ephedrine mixed with my daily meds produces almost a narcotic-like effect. ncbi. 112796. It was like I was seeing a layer of fat burn each day. So I'd been taking ephedrine/caffeine combo (25mg/200mg) 1 time a day for about a month straight when I noticed a ton of upper right abdomen pain. I'd be more worried about potential cardiovascular effects than any negative psychological damage from using pseudoephdrine long term. Occasional stimulant use can work but they're incredibly addictive. tldr Long term exposure to ephedrine, which is similar to pseudo-ephedrine thats in Zytec or Allegra-D, etc leads to neurotoxicity. But to reiterate the water / peroxide comparison is wrong. Sublingual dosing works best for that application, can last upwards of 14 hours orally. doi: 10. As long as you're a young, able bodied person it is going to have very little in adverse effects. The discussions were mostly anecdotal, and I remain uncertain about the overall scientific consensus on Long term (1 year or more) daily users of Pregabalin for anxiety - I have some questions for you. Ephedrine has no real interaction with serotonergic systems and only mild changes in dopaminergic systems. It is able to induce fat loss via increasing the amount of fat available for fuel as well as by increasing heat expenditure. There're no major studies about the effects of ephedrine with regards to long-term weight-loss. I was in a deficit and worked hella hard, but clen def helped. Long term use of ephedrine and pseudo-ephedrine is linked to heart and liver failure. nih. I believe this substance is controlled but legal in most parts of the United States (no Ephedrine has long been used as an appetite suppressant and pure ephedrine was banned by the FDA back in the early 2000’s because long term use can cause serious cardiac issues. The pharmacology of valerian suggests it can potentially become addictive. When you start taking 200mg caffeine and 24mg ephedrine 3x per day, some days you wake up feeling like shit. Find a way to eat and exercise that you can LIVE WITH in the LONG TERM. Cuz ur dosage was already so low, pause wasnt long, additionally u said it happened a week after u re-took it not the same day, it all points to placebo (fake) side-effects. I've heard about high blood pressure issues that it can cause, but when I check it, it never comes out high at all. I've heard that ephedrine can cause kidney stones if used for long enough. Saw this post in the nootropics subreddit: link. I cycled off for short periods of times a couple of time over the years thinking it would help my tolerance (I guess it did a little) but it clearly doesn't do much for me anymore. But CONSISTENCY in your first few years of this weight loss journey will be the most important. Jun 29, 2018 · So, if you are worried about long term use of Sudafed causing your nasal congestion to worsen, that won't happen for the vast majority of individuals. Does long term antidepressant usage shorten lifespan like how anti-psychotics use shortens your life for 25 years? Like if you used a antidepressant for more than a year and for a decade and more is that going to cut your life span in half and potentially ruin and damage your organs permanently? You should look into ephedrine, it likely has very similar effects/benefits but it is well studied and well established for use as a preworkout stimulant. Depends on state. I constantly ask my doctor and therapist if what I'm doing is ok. I’ve seen some people use it for 2-3 months with no noticeable negative side effects, and was wondering what the general consensus of this substance is. Cancellation effect is very strong. Induction of general anesthesia and ongoing anesthesia during operative cases results in vasodilatation and hypotension, requiring treatment A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. Jan 1, 2005 · OBJECTIVE: As part of a synthesis of evidence regarding the efficacy and safety of ephedra, the authors describe data on psychiatric adverse events from reports submitted to the Food and Drug Administration (FDA). The long-term use of oral decongestants at therapeutic dosages is not linked to dementia in any way. By itself it’s just a fluke, speaking Any sort of permanent changes to my personality and/or the way I think even when the stimulant is supposed to have worn off (I've read some frightening accounts of people who claim that long term stimulant use rewired their brains - either making them less humorous, more robotic, less creative, more analytical and less emotional, unable to feel Apr 21, 2023 · I reviewed ten sources from Reddit discussions on various aspects of ephedrine, mainly focusing on its potential as a nootropic. May 6, 2024 · Learn about the side effects of ephedrine, from common to rare, for consumers and healthcare professionals. It can help in weight loss but the side effects are too serious to use for this purpose (long-term use is necessary to achieve the effect). Is this true? If so, is there any way to prevent it? Are there any other potential health risks with semi long-term ephedrine use? ive been taking ephedrine for 20+ years, i never get the energy effect anymore (i feel yohimbine preworkouts way more), it still helps me breathe for an hour or two though. After 8-weeks of exposure to ephedrine, the toxic effects of ephedrine included significant weight loss and induction of behavioral changes in rhesus macaques. gov/8384187/ Int J Obes Relat Metab Disord 1993 Feb;17 Suppl 1:S73-8. Other than that for anxiety u dont need to use it daily, unless u are required to talk in front of people every day, but use them as-per-needed (before fearful social events). Comparing a test cycle against year long ephedrine when the former damages the liver and HPT axis whereas the latter damages the cardiovascular system? Throwaway account But a few years ago (probably 3-4) I started using ephedrine and caffeine to help with weight loss. 2 MJ/day) and either an ephedrine/caffeine combination (20mg/200mg), ephedrine (20mg), caffeine (200mg) or placebo 3 times a day for 24 weeks. I'm using the ECA stack for increased energy and as an appetite suppressant. i don’t have a lot of the side effects that can be experienced, so i’m not as bothered as some people are. You can almost feel it. Cardiovascular Effects Of Sudafed Ephedrine makes up about 30-90% of the total alkaloid content. It’s just another gimmick. Fifty-seven Yes I’ve used it during grad school years ago when I didn’t have a prescription for a stimulant. ) Afrin however is a vasoconstrictor, feels amazing for first week but your body gets used to it, and long term use actually makes the inflammation bounce back even worse. Also, if your doctor wants you to stop using pseudo it's not out of line to ask him for something else that could reduce the side effects of your medication. It's the most effective supplement there is. 40 mg ephedrine, 200 mg caffeine and 150 mg aspirine 2x-3x daily. IF you're going to bars on ephedrine, watch out for the sweating. It has been implicated in increasing the metabolic rate by up to 5% in humans. Yep, Lyle Mc has articles on long-term use and how it only increases in effectiveness. I used to use magnesium, but my doctor HS me on Miralax and stool softeners and fiber and I still need to use the occasional glycerin suppository. I used valerian for a week consecutively at one point and now I use it everrrry now and then for sleep or pain issues, but it is not my first choice. In particular, in the modeling group, the abnormal behavioral changes mainly manifested as irritability and behavioral sensitization. I’ve been using ephedrine (8mg) for well over a year, Daily doses depending, maybe 16mg-24mg in the morning And 16mg (2) -24mg (3) pre-workout. Ephedrine derives most of its effect from beta-adrenoreceptors while meth interacts with the TAAR GPCRs, those classes of receptors, and their down stream effects are wildly different. Most states are this way. g. May 8, 2023 · Ephedrine is a medication used to manage and treat clinically significant hypotension. All medica … It's almost impossible to take it long-term and still see benefits (at least to take it continually long term) as a beta-2 antagonist as your receptors become saturated pretty quickly and you'll need to take off a week or two for every two weeks that you take it to get it working as well as it should be (has a long half-life). But there's very little research on long-term "moderate" cocaine users. I do my best not to take enough to get high and don't exceed a certain dose at a time or redose more than necessary. However, you need to consider the other effects Sudafed has on the body (e. So 1 gram of ma huang will contain between 10 and 30mg of alkaloids. It is unclear how much ephedrine or other agents would have to be consumed to create a stone. Its controlled (requires ID + signature) like cold formula with pseudo-ephedrine, but still legal for asthma related use. source. Daily totals: ephedrine (75-150mg), caffeine (150mg) and aspirin (330mg), Divide up and consume before meals. 25 mg 1-3 times a day you can start lower if you want but keep in mind it raises your liver enzymes so don’t overdo it long term Jcaesar369 • Khaliftsi • Additional comment actions all bitter orange is is synephrine and there's not been as much (or any?) long term research done on it within the realm of fat loss and long term safety like has been done on ephedrine. Long-term cocaine use is almost certainly negative because of it's high cardiotoxicity. Definitely not something I would do as recreational drug, too many side effects and I never really got addicted to ephedrine because of that. I went from 15-10% in 2 weeks on clen. Likely what you have is an herbal form or ephedrine hydrochloride. People with anorexia would use Adderall to suppress their hunger pangs so they can feel more comfortable in not eating, and this can cause many long term health consequences. Best to avoid vasoconstrictors unless you need it in extreme need. METHOD: The authors reviewed all 1,820 adverse event reports related to dietary supplements containing herbal ephedra from FDA MedWatch files as of Sept. Not a place for discussion of illicit and illegal compounds. With bupropion being an NRI and ephedrine stimulating noradrenaline release, it may be overstimulating. Considering the frailty of an anorexic heart, this can even be fatal. Tressless (*tress·less*, without hair) is the most popular community for males and females coping with hair loss. 2020. I never do any hard cardio on it but sometimes I use it as a pre-workout. Only around 5 hours sublingual I understand that it’s fairly cardio toxic as well as carrying a few other different long term risks. Don’t know much about its long term use impact but I think like with any medication, it’s to good to take breaks and cycle off from time to time so as not to become dependent. For the past month or so I’ve been taking 6x4mg Ephedrine HCL pills with my pre-workout (200mg caffeine). 064% of all stones analyzed in one study), but questioning patients about herbal ephedrine use should be considered (Powell et al, 1998). I can also highly vouch for phenylpiracetam as a workout drug. I do all sorts of combos I like. So start with 12. Reply reply Sep 1, 2020 · Long-term exposure to ephedrine leads to neurotoxicity and neurobehavioral disorders accompanied by up-regulation of CRF in prefrontal cortex and hippocampus in rhesus macaques Behav Brain Res . 2-3 gms L-citrulline with 50-100mg bacopa is also very relaxing. 5 mg twice per day than add in 12. It doesn't start from the first day, but after a few days. I cannot fucking shit normally because of abusing laxatives for so long. The symptoms were as follows: constant yawning, sleep for 14 hours, constant feeling of sleepiness, problems with short-term memory, long-term memory. I'd suggest taking a minimum dose necessary to kill your appetite to start then increase dosing down the line. I use it for like 8-10 weeks a year. Like any intellectual lifter, I’m here for advice on the use of stimulants. It still kicks me in the ass (good way) every time I take it, totally depending on the day I maybe only take 2-3 tabs once and be good. The intellect was greatly reduced and I couldn't solve even simple tasks. It is in the sympathomimetic class of drugs. The FDA-approved primary indication for ephedrine is the treatment of clinically significant hypotension perioperatively. And I think the biggest long term "benefit" is reducing stress over the long term. If only 30-90% of that is actual ephedrine, that means anywhere between roughly 3mg and 27mg of ephedrine per gram of ma huang. I will use ephedrine or adderal maybe once or twice a month when I really need to hammer on a project. Negative side-effects from long-term Ephedrine use? I've been using 25 mg ephedrine with 150-200 mg caffeine 1-2x daily for 3 months now. Especially if I have not used meth or any other stimulants in a long time. Yes, ephedrine may help you to lose weight, but there's no evidence that it's safe. So, probably OK; may want to keep an eye on BP / heart rate etc if using long term. increase in blood pressure) and there are some precautions to take. Initially I thought it was my gallbladder because of my rapid weight loss, but I had an ultrasound and it was clear of stones. That makes you lose weight too but its definetely not a tactic you'll find recommended by anyone but the shadiest modelling agent (apparently that does happen. 5mg doses thereafter I would be careful with long term use of valerian in contexts such as everyday use. Jan 20, 2017 · The authors of one analysis concluded that supplements containing ephedra and ephedrine trigger modest short-term weight loss (about 2 pounds per month more than placebo). But none of the 52 trials they looked at lasted more than six months, so there is no evidence to support ephedra use for long-term weight loss. I am now 28 years old, around 8 years of lifting under my belt and I consistently stay around 205lbs. It will not help muscle growth. Use for 3 days max and not more than 4 times a year I would say. this treatment plan has helped me to cope with some of the biggest adhd symptoms i experience, which allows for me to live a fairly “normal” life. You'll have more energy but it will be terrible for your mental and physical health in the medium to long term. Ephedrine has a considerably low therapeutic index, a rather "dirty" receptor binding profile, and builds tolerance very quickly. I fuckin love how extra tweaked out the Ephedrine makes me feel, and how much more I sweat. Under normal conditions, women are less likely to experience hair loss than men due to having fewer circulating androgens, but when females supplement testosterone, such as in those transitioning female-to-male, they actually experience a higher rate of hair loss than men who take similar amounts of testosterone, taking into account body size. GABA & glycine make a great combo to replace l-theanine. Drug addiction continues to threaten the health and welfare of people worldwide, and ephedrine abuse is a serious drug problem in many areas of the world. Feel free to discuss remedies, research, technologies, hair transplants, hair systems, living with hair loss, cosmetic concealments, whether to "take the plunge" and shave your head, and how your treatment progress or shaved head or hairstyle looks. ezhb rrxampj zcxb qfmjfk mdh edqn maqif izz uqh vqvpfqy
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